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目的探讨重症监护病房(ICU)患者动脉血乳酸检测在预后评估中的作用。方法 84例危重病患者作为研究对象,对其动脉血乳酸浓度进行检测,并根据血乳酸检测结果将84例患者分为正常组(血乳酸<2.4 mmol/L)、中度增高组(2.4 mmol/L<血乳酸<8.1 mmol/L)和高度增高组(血乳酸>8.1 mmol/L),并比较三组患者的预后情况。结果本次正常组患者33例,中度增高组患者27例,高度增高组患者24例。中度增高组和高度增高组患者的血乳酸浓度、病死率[(4.77±1.45)mmol/L、55.56%,(10.15±2.71)mmol/L、83.33%]均高于正常组[(1.74±0.53)mmol/L、15.15%],差异均具有统计学意义(P<0.05);且高度增高组患者血乳酸浓度、病死率均高于中度增高组,差异均具有统计学意义(P<0.05)。结论动脉血乳酸检测结果是提示危重病患者疾病严重程度的重要指标,对患者的预后评估具有十分重要的临床价值。
Objective To investigate the role of arterial blood lactic acid in prognosis assessment in intensive care unit (ICU) patients. Methods A total of 84 critically ill patients were enrolled in this study. The levels of arterial blood lactate were determined. According to the result of blood lactate test, 84 patients were divided into four groups: normal group (2.4 mmol / L), moderate group / L 8.1 mmol / L). The prognosis of three groups were compared. Results The normal group of 33 patients, moderate increased group of 27 patients, elevated group of 24 patients. Compared with the normal group [(1.74 ± 2.45) mmol / L, the lactic acid concentration, the mortality rate were significantly higher in the moderately elevated group and the highly increased group (4.77 ± 1.45 mmol / L, 55.56%, 10.15 ± 2.71 mmol / L, 83.33% 0.53) mmol / L, 15.15%], the differences were statistically significant (P <0.05); and the patients with elevated hyperplasia had higher levels of lactic acid and fatality than those with moderate hyperproliferation (P < 0.05). Conclusion The result of arterial blood lactate test is an important indicator of the severity of disease in critically ill patients and has very important clinical value in the prognosis evaluation of patients.