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[目的]探讨雄黄引起急性中毒的原因。[方法]分析4例急性、亚急性砷中毒病例,以及有关雄黄毒性和中毒病例文献报道。[结果]本文3例亚急性砷中毒的主要原因可能与雄黄中三氧化二砷(As2O3,俗称砒霜)含量过高有关,1例急性砷中毒可能与超量食用致摄入雄黄中杂质As2O3过多及加热造成雄黄中As2O3含量增加有关。[结论]使用劣质雄黄、超量及加热后食用雄黄,可引起急性、亚急性砷中毒甚至死亡,应引起重视。
[Objective] To investigate the cause of acute poisoning caused by realgar. [Method] Four cases of acute and subacute arsenism were analyzed, and the reports about the virulence and poisoning of realgar were reported. [Results] The main causes of subacute arsenic poisoning in 3 cases may be related to the excessive content of As2O3 (As2O3), one case of acute arsenic poisoning may be caused by over-consumption of too much impurity As2O3 in realgar and heating Ascorbate caused by the increase in As2O3 content. [Conclusion] The use of realgar, excessive consumption of realgar and heating, can cause acute and subacute arsenic poisoning and even death, which deserves great attention.