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目的:观察孟鲁司特钠对成人轻至中度支气管哮喘患者的心理情绪影响。方法:将44例临床诊断为支气管哮喘的患者随机分为2组,观察组每晚睡前使用孟鲁司特钠10mg;对照组早晚各一次应用酮替芬1 mg。比较2组惠者用药前后临床疗效及心理情绪的变化。结果:对照组与观察组相比,平均每周哮喘发作次数,夜间憋醒次数,焦虑评分,抑郁评分均有明显改善,差异有显著性(P<0.05)。结论:孟鲁司特能有效控制哮喘症状,减轻患者的不良心理情绪影响。
Objective: To observe the influence of montelukast on the mood of adults with mild to moderate bronchial asthma. Methods: Forty-four patients with bronchial asthma were randomly divided into two groups. The observation group received 10 mg of montelukast sodium every night before bedtime. The control group received ketotifen 1 mg one time sooner or later. Compare the two groups of beneficiaries before and after treatment of clinical efficacy and psychological changes. Results: Compared with the observation group, the mean number of asthma attacks, nocturnal awakening, anxiety scores and depression scores in the control group and the observation group were significantly improved (P <0.05). Conclusion: Montelukast can effectively control the symptoms of asthma and relieve the adverse psychological mood of patients.