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例1女,9岁。因发热,伴头痛、呕吐20天。体检:T39.4℃,P96,R23,BPl4/9kPa。发育营养正常,神靡,颈部触及黄豆大淋巴结3枚,无触痛。双侧瞳孔等大等圆,对光反射存在,左眼球轻度外展。心肺体检未见异常,肝脾均未触及。颈项抵抗,克氏征(+),布氏征(+)、巴氏征(一)。眼底检查双侧视乳头水肿。血常规:Hb 116g/L、WBCl0.1×10~(9)/L、N:0.68。脑脊液:无色透明,潘氏试验阳性,蛋白1.5g/L,细胞数226×10~(6)/L,氯化物108mmol/L、糖4.8mmol/L,薄膜试验(一)。脑脊液培养有霉菌生长,墨汁染色找到新型隐球菌,确诊为新型隐球菌脑膜炎。
Example 1 female, 9 years old. Due to fever, with headache, vomiting for 20 days. Physical examination: T39.4 ℃, P96, R23, BPl4 / 9kPa. Development of normal nutrition, god extravagant, the neck touched the big three lymph nodes, no tenderness. Bilateral pupils and other large circle, the presence of light reflex, the left eye slightly outreach. No abnormal cardiopulmonary examination, liver and spleen were not touched. Neck resistance, Kirschner sign (+), Buchner sign (+), Pakistan sign (a). Fundus examination bilateral papilledema. Blood: Hb 116g / L, WBCl0.1 × 10 ~ (9) / L, N: 0.68. Cerebrospinal fluid: colorless and transparent, Pan test positive, protein 1.5g / L, the number of cells 226 × 10 ~ (6) / L, chloride 108mmol / L, sugar 4.8mmol / L, the film test (a). Cerebrospinal fluid culture has mold growth, ink stain found Cryptococcus neoformans, diagnosed as Cryptococcus neoformans meningitis.