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目的:探索心型游离脂肪酸结合蛋白在急性非ST抬高心肌梗死超早期(小于3 h)的应用价值。方法:选取2009年-2011年我院就诊的127名NSTEMI患者,以急诊PCI术中造影结果、冠状动脉CTA结果以及发病后3个月随访等信息作为最终诊断,在发病超早期内定性测定H-FABP及定量测定cTnI,并进行统计。结果:在本研究入组的患者中,H-FABP与cTnI相比具有较好的敏感性和特异性;联合H-FABP与cTnI两项结果进行诊断,其敏感度、特异性、阳性预测值及阴性预测值均较高。结论:H-FABP有望作为急性心肌坏死监测的一项快速、准确、敏感、特异性的指标。
Objective: To explore the value of cardiogenic free fatty acid binding protein in ultra-early (less than 3 h) acute non-ST-elevation myocardial infarction. Methods: A total of 127 patients with NSTEMI admitted to our hospital from 2009 to 2011 were enrolled in this study. The diagnostic results of emergency PCI, CTA and 3-month follow-up were used as the final diagnosis. H -FABP and quantitative determination of cTnI, and statistics. Results: H-FABP had better sensitivity and specificity than cTnI in the patients enrolled in this study. The sensitivity and specificity of H-FABP and cTnI in diagnosis were higher than those in cTnI And negative predictive value were higher. Conclusion: H-FABP is expected to be a fast, accurate, sensitive and specific indicator for the monitoring of acute myocardial necrosis.