论文部分内容阅读
目的：研究良性淋巴上皮病变及其恶变中上皮性成分，探讨其发生、发展及诊断等问题。方法：采用免疫组化染色方法。结果：良性淋巴上皮病变中上皮岛构成细胞大部分HHF35呈阴性，仅在外周可见少许HH35阳性细胞。而AE1／AE3抗体在上皮岛构成细胞中大部分呈阳性。恶性淋巴上皮病变中癌巢内AE1／AE3抗体呈弥漫阳性，HHF35抗体主要分布在癌巢外周细胞。结论：BLEL起源于增生的导管，上皮岛构成细胞主要是导管上皮细胞，BLEL恶性发展成MLEL时，导管上皮增生，外周肌上皮细胞也增生。
Objective: To study the benign lymphoepithelial lesion and its malignant epithelial components, to discuss its occurrence, development and diagnosis. Methods: Immunohistochemical staining method was used. Results: Most of epithelial island cells in benign lymphoepithelial lesions were negative for HHF35, and only a few HH35 positive cells were seen in the periphery. The AE1 / AE3 antibodies in the epithelial island constitute the majority of cells were positive. AE1 / AE3 antibodies in neoplastic neoplasms of malignant lymphoepithelial lesions were diffusely positive, while HHF35 antibodies were mainly located in peripheral neoplasms of cancer nests. CONCLUSION: BLEL originated from hyperplasia of ductal epithelial cells. Epithelial island formed cells were mainly ductal epithelial cells. When BLEL developed malignantly into MLEL, ductal epithelial hyperplasia and peripheral myofibroblast also proliferated.