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本文就下列有助于血吸虫疫苗发展的一些流行病学问题作了介绍。1.血吸虫病的感染和分布:现已证实血吸虫病流行于75个国家,患病人数约2亿,受威胁的人口约5～6亿。曼氏血吸虫和埃及血吸虫存在于53个国家。40个有曼氏和埃及血吸虫病流行的国家和6个有间插血吸虫病流行的国家对血吸虫疫苗感兴趣。2.感染的分类:目前应用于流行病学调查的定量技术主要有Kato法和尿过滤法。虽然应用这些方法能定量地分析感染度,但并不能反映感染的全部情况。3.各
This article presents some of the epidemiological issues that have contributed to the development of the schistosome vaccine. 1. Schistosomiasis infection and distribution: It has been confirmed that schistosomiasis is endemic in 75 countries and has a disease population of about 200 million and a threatened population of about 500 million to 600 million. Schistosoma mansoni and S. schistosome exist in 53 countries. Of the 40 countries where Manchurian and Egyptian schistosomiasis are endemic and 6 countries with an epidemic of inter-schistosomiasis are interested in schistosome vaccine. 2. Classification of Infections: Quantitative techniques currently used in epidemiological investigations include Kato’s method and urinary filtration method. Although the application of these methods can quantitatively analyze the degree of infection, but does not reflect the full extent of the infection. 3 each