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目的 为了探讨2 ～7 岁儿童体内骨矿含量与其生长发育的关系。 方法 运用单光子吸收技术(SPA) ,随机测量了298 名健康儿童的右桡骨骨矿含量,同时进行了人体测量。 结果 运用所测得参数,采用离差均数法建立了上海地区2 ～7 岁健康儿童的骨矿含量(BMC) 正常值参考范围;发现小儿BMC 与年龄、身高、体重呈显著正相关( P 均< 0 .01) ;由此建立了骨矿含量随小儿年龄和身高、体重变化的直线方程。还发现在固定身高、体重两因素后,年龄与BMC 的正相关将失去显著性。身高、体重与骨矿含量的关系被表达成标准的百分图形式,此预测图可用来估计经身体大小调节后的预测值,及用来比较说明实际值与预测值的不同。 结论 骨矿含量与儿童生长发育有密切关系;适当运用预测图可更有利于将SPA 用于正确监测和治疗儿童骨生长和代谢性疾病
Objective To explore the relationship between bone mineral content and its growth and development in children aged 2 to 7 years. Methods Single photon absorption (SPA) technique was used to measure the content of right radius bone in 298 healthy children at the same time. Results By using the mean-deviation method, the reference range of normal bone mineral content (BMC) of healthy children aged 2 ~ 7 years in Shanghai was established by using the measured parameters. There was a significant positive correlation between BMC and age, height and weight All <0 .01); thus established a linear equation of bone mineral content with the age and height, weight changes of children. Also found in the fixed height, weight, two factors, age and BMC positive correlation will lose significance. The relationship between height, body weight and bone mineral content is expressed as a standard percentage graph. This predictive graph can be used to estimate body-size-adjusted predictors and to compare the differences between actual and predicted values. Conclusion Bone mineral content is closely related to the growth and development of children. Appropriate use of predictive maps may be more useful for the proper monitoring and treatment of bone growth and metabolic diseases in children