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目的 :探讨肿瘤病人的心理社会因素与免疫功能的相关性。方法 :用病例对照和多因素统计分析方法 ,对 37例肿瘤病人和 37例非肿瘤病人进行了心理社会因素调查并检测其免疫功能 ,分析其间的相互关系。结果 :肿瘤病人与非肿瘤病人相比免疫功能明显减退 ,主要表现为IgM、CD16+ 水平的减少 (P <0 0 1 ) ,肿瘤病人的IgM、CD3 + 与负性生活事件、社会支持、抑郁情绪等因素相关。结论 :肿瘤病人的免疫功能低下主要表现在IgM ,CD16+ 水平的减少。负性生活事件、社会支持、情绪抑郁等心理社会因素对肿瘤病人的免疫功能影响较大
Objective: To investigate the correlation between psychosocial factors and immune function in cancer patients. Methods: Using case-control and multivariate statistical analysis, 37 cases of cancer patients and 37 cases of non-tumor patients were investigated for psychosocial factors and their immune function was tested, and the correlation between them was analyzed. Results: Compared with non-tumor patients, the immune function of patients with tumors was significantly reduced, mainly as the decrease of IgM and CD16 + (P <0.01), IgM, CD3 + and negative life events, social support, depression Related factors. CONCLUSION: The immunocompromised patients with tumor mainly manifest in the decrease of IgM and CD16 + levels. Negative life events, social support, depression and other psychological and social factors on immune function of tumor patients greater impact