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目的探讨胰腺癌ERCP所见与肿瘤大小和分期的关系。方法选择手术和病理证实为胰腺癌、ERCP影像清晰的患者35例,根据ERCP片子测量主胰管和胆总管狭窄长度,并测量胰胆管梗阻远端直径。将胰腺癌肿瘤大小(TS)和JPS T分类与ERCP所见的关系进行相关性分析。结果35例中25例ERCP主胰管狭窄,10例中断(7例导丝通过梗阻部位显示病变长度),31例胆总管狭窄。35例肿瘤大小与胰管和胆总管狭窄长度的相关系数分别为0．709(P=0．0001)和0．540(P= 0．0053),JPS T分类与胰管狭窄长度的相关系数为0．514(P=0．0052)。结论胰腺癌ERCP胰管狭窄长度与肿瘤大小和分期呈正相关,但狭窄段短者与肿瘤大小及分期并非完全一致,胆管狭窄长度对预测胰头肿瘤大小亦有作用。
Objective To investigate the relationship between ERCP findings and tumor size and stage in pancreatic cancer. Methods Thirty-five patients with clear ERCP were selected surgically and pathologically. Pancreatic duct and common bile duct stenosis length were measured by ERCP and the distal diameter of pancreaticobiliary obstruction was measured. Correlations between pancreatic cancer size (TS) and JPS T classification and ERCP findings were analyzed. Results Twenty-five cases of ERCP had pancreatic duct stenosis, 10 cases of interruption (7 cases of lesion length showed through the obstruction site) and 31 cases of common bile duct stenosis. The correlation coefficients between tumor size and length of pancreatic duct and common bile duct stenosis were 0.709 (P = 0.0001) and 0.540 (P = 0.0053) respectively. Correlation coefficients between JPS T classification and length of pancreatic duct stenosis Was 0.514 (P = 0.0052). Conclusions The length of pancreatic duct ERCP in pancreatic cancer is positively correlated with tumor size and stage. However, the short segment of the pancreatic duct is not exactly the same as the size and stage of the tumor. The length of bile duct stenosis also plays an important role in predicting the size of the pancreatic head.