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作者已经报导延胡索乙素(简称乙素或THP)有良好的镇痛效能和明显的镇静催眠作用,并为临床证明。对内脏钝痛的缓解有较好的效果,而服用其中短程的催眠剂量时,未发现有头昏、头晕等不良的后作用,可以认为乙素是具有一定实际价值的药物。因此,有必要探讨乙素在机体内代谢情况,以利于合理用药,及其作用机制的阐明。本文即报导乙素在体内吸收、分布、排泄的资料、以及巴马汀在体内转化的一些研究结果。
The authors have reported that tetrahydropalmatine (B or THP for short) has a good analgesic efficacy and significant sedative and hypnotic effects, and for clinical evidence. On the visceral dull pain relief has a good effect, and taking short-term hypnosis dose, did not find dizziness, dizziness and other adverse effects, you can think of B is a certain practical value of the drug. Therefore, it is necessary to explore the metabolism of B in the body, in order to facilitate the rational use of drugs, and clarify its mechanism of action. This article reports on the absorption of B in vivo, distribution, excretion of information, and some of the results of the conversion of palmatine in vivo.