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目的 :探讨 2型糖尿病患者微量白蛋白尿与缺血性心脏病 (IHD)的关系。方法 :6 1例 2型糖尿病患者 ,依有无并发 IHD分为糖尿病并 IHD组 (17例 )和糖尿病不并 IHD组 (44例 ) ,分析比较两组心血管疾病危险因素。再依微量白蛋白尿含量分为微量白蛋白尿组 (2 2例 )和非白蛋白尿组 (39例 ) ,比较两组 IHD的发生率。结果 :糖尿病并 IHD微量白蛋白尿含量明显高于不并 IHD组〔(98.5 1± 48.97) m g/L∶ (9.87± 5 .84) mg/L ,P <0 .0 1〕;微量白蛋白尿组并发 IHD的发生率显著高于非白蛋白尿组 (45 .45 %∶ 17.95 % ,P<0 .0 5 )。结论 :检测微量白蛋白尿是预测 2型糖尿病患者 IHD发病率的有意义的指标。
Objective: To investigate the relationship between microalbuminuria and ischemic heart disease (IHD) in type 2 diabetic patients. Methods Sixty-one patients with type 2 diabetes mellitus were divided into diabetic and IHD group (n = 17) and non-diabetic and non-diabetic IHD group (n = 44) according to the presence of non-concurrent IHD. Risk factors for cardiovascular disease were analyzed. According to the microalbuminuria, the patients were divided into microalbuminuria group (22 cases) and non-albuminuria group (39 cases). The incidence of IHD was compared between the two groups. Results: The urinary albuminuria in patients with diabetes mellitus was significantly higher than that in the non-IHD patients (98.5 ± 48.97 mg / L, 9.87 ± 5.84 mg / L, P <0.01) The incidence of IHD in urinary group was significantly higher than that in nonalbuminuria group (45.45%: 17.95%, P <0.05). CONCLUSIONS: The detection of microalbuminuria is a meaningful indicator of the incidence of IHD in patients with type 2 diabetes.