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1983年本刊曾设专栏介绍钙拮抗剂,时经四年,有关钙拮抗剂的研究与应用更为广泛深入,Braunwald指出,钙拮抗剂代表着本世纪后期最重要的心血管病治疗进展之一.近年来以钙拮抗剂为主题的国际会议与专辑不少,Am J Cardiol最近二期专辑(1987年Vol 59,No.2,3)比较全面地概括钙拮抗剂在临床应用方面的进展,本期将有关钙拮抗剂在心绞痛、心肌梗塞、高血压、心律失常、肥厚型心肌病、心力衰竭、粥样硬化等方面的应用现况分别介绍.多年来,此类药物的名称和分类方法颇不一致.为此,世界卫生组织于1985年指定专家委员会加以讨论.根据历史和临床应用简便的理由,认为“钙拮抗剂”一词比“钙通道阻滞剂”“钙进入阻滞剂”等词为优.根据各种钙拮抗剂的化学性质,可以分为二大类六小类.此种归纳有助于进一步理解和应用.
In 1983, we published a column introducing calcium antagonists. After four years of research and application of calcium antagonists, Braunwald pointed out that calcium antagonists represent the most important cardiovascular disease treatment in the latter part of the century In recent years, many international conferences and albums on the theme of calcium antagonists, Am J Cardiol recent two albums (1987 Vol 59, No.2,3) a more comprehensive overview of the clinical application of calcium antagonists in the progress This issue describes the use of calcium antagonists in angina, myocardial infarction, hypertension, arrhythmia, hypertrophic cardiomyopathy, heart failure, atherosclerosis, etc. For many years, the names and classifications of these drugs The methodology is quite inconsistent, and for this reason, the WHO commissioned a committee of experts to discuss it in 1985. According to historical and clinical reasons for simplicity, it is believed that the term “calcium antagonist” is better than “calcium channel blocker” Calcium entry blocker "and other words as excellent.According to the chemical properties of various calcium antagonists, can be divided into two categories six small class.This induction will help further understanding and application.