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目的:通过EQ-5D量表中EQ-5D健康描述系统和EQ-VAS(直观相似尺度)评分对急性缺血性脑卒中患者健康相关生存质量测量的相关性进行研究。方法:采用前瞻性的随机对照试验设计,对220例急性缺血性脑卒中患者从就诊第0天、第8天、出院至第90天的生存质量和健康状况,运用EQ-5D健康描述系统和EQ-VAS进行研究。结果:以EQ-5D指数得分(健康描述系统评分)和EQ-VAS得分对患者四个阶段生存质量的表达进行线性回归模型拟合,发现两者对患者生存质量的表达趋势一致;进而进行的无控制变量和有控制变量(教育程度和从事职业)的相关性分析显示两者的相关系数均较高(>0.500;P=0.000),且相关性的稳定性也较好。结论:EQ-5D健康描述系统和EQ-VAS的相关性较好,两者的配合使用适用于我国急性缺血性脑卒中患者生存质量和健康状况测量,能够反映其变化情况,也适宜做进一步的成本-效用分析。
OBJECTIVE: To investigate the association of health-related quality of life measures in patients with acute ischemic stroke by the EQ-5D Health Description System and the EQ-VAS (Intuitive Similarity Scale) scale in the EQ-5D scale. METHODS: A prospective, randomized, controlled trial was designed. The quality of life and health status of 220 patients with acute ischemic stroke from the first day of treatment, the eighth day of discharge, the discharge to the 90th day of treatment were analyzed using the EQ-5D health description system And EQ-VAS. Results: EQ-5D index score (health description system score) and EQ-VAS score of the four stages of patients with quality of life expression of linear regression model fitting and found that both the quality of life of patients with the expression of the trend; then Correlation analysis between uncontrolled variables and control variables (education and career) showed a high correlation coefficient (> 0.500; P = 0.000) and a good correlation. Conclusion: The correlation between EQ-5D health description system and EQ-VAS is good. The combination of EQ-5D and EQ-VAS can be used to measure the quality of life and health status in patients with acute ischemic stroke in our country, which can reflect the changes and is suitable for further Cost-effectiveness analysis.