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在１０只犬的实验性心肌梗塞模型上进行心肌断层显像与容积定量分析，对照病理解剖资料评价主要定量参数心肌缺损体积（ＤＶ）及缺损范围分数（ＤＦ）的准确性；另２１只犬分为对照组和Ｎｄ：ＹＡＧ激光心肌血管重建术（ＴＭＲ）组；分别进行实验性心肌梗塞术后心肌断层定量显像。结果表明：病理解剖定量分析获得的心肌梗塞区体积（ＩＶ）与心肌血流断层定量结果ＤＶ值具有良好相关（ｒ＝０．８８），两种方法所计算的心肌病变范围分数（ＤＦ）无显著性差异（Ｐ＞０．０５）。ＴＭＲ组实验犬其ＤＦ值明显小于心梗对照组（Ｐ＜０．０５），分别为２７．５％± ３．９％和３２．１％±４．６％。结果提示：~（９９ｍ）Ｔｃ－ＭＩＢＩ心肌断层定量显像能较准确地判断心肌血流及病变范围，是一种较好的冠心病诊断及疗效评价方法，Ｎｄ：ＹＡＧ ＴＭＲ治疗具有改善缺血心肌血流灌注及缩小心肌梗塞范围的作用。
Myocardial tomography and volumetric quantitative analysis were performed on experimental myocardial infarction models in 10 dogs. The accuracy of the major quantitative parameters of myocardial defect volume (DV) and defect size fraction (DF) was evaluated according to the pathological anatomy data. The other 21 dogs Divided into control group and Nd: YAG laser myocardial revascularization (TMR) group; myocardial infarction after myocardial infarction quantitative imaging. The results showed that the volume of myocardial infarction area (IV) obtained by pathological anatomical quantitative analysis was positively correlated with the DV value of myocardial blood flow fault (r = 0.88), and the calculated range of myocardial lesions (DF) Significant difference (P> 0.05). The DF value of TMR group was significantly lower than that of myocardial infarction group (P <0.05), which were 27.5% ± 3.9% and 32.1% ± 4.6%, respectively. The results suggest that ~ (99m) Tc-MIBI myocardial perfusion quantitative imaging can accurately determine the extent of myocardial blood flow and lesions, which is a good method for the diagnosis and evaluation of coronary heart disease. Nd: YAG TMR treatment has the effects of improving ischemia Myocardial perfusion and reduce the scope of myocardial infarction.