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用免疫组化方法检测胃癌组织中的P53和P185蛋白表达，结果表明P53和P185基因表达与胃癌患者性别，年龄，肿瘤部位，肿瘤分期，病理类型等均无明显关系，而P53基因阳性表达胃癌患者的生存期低于P53基因阴性表达者。P185基因表达与胃癌患者的生存期无关，提示P53表达可能对判断胃癌预后有一定的作用，而多基因同时异常表达可能对临床估计预后更有意义。
Immunohistochemistry was used to detect the expression of P53 and P185 proteins in gastric cancer tissues. The results showed that the expression of P53 and P185 genes had no significant relationship with gender, age, tumor location, tumor stage, pathological type, etc., while P53 positive expression gastric cancer. Patients have lower survival than those with negative P53 expression. The expression of P185 gene was not related to the survival time of gastric cancer patients, suggesting that the expression of P53 may have a certain effect on judging the prognosis of gastric cancer, and the abnormal expression of multiple genes at the same time may be more meaningful for clinically estimated prognosis.