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目的分析同型半胱氨酸(Hcy)与H型高血压的关系。方法 66例H型高血压患者(Hcy>10μmol/L)作为观察组,选择同期66例入院体检的健康者(Hcy<10μmol/L)作为对照组。采用酶循环法测定两组研究对象的血浆总同型半胱氨酸水平。比较两组研究对象Hcy水平及心脑血管事件发生率,比较观察组不同危险患者Hcy水平。结果入院时、1个月后、3个月后,观察组Hcy水平均高于对照组,差异具有统计学意义(P<0.05);观察组患者心脑血管事件发生率为22.73%,明显高于对照组的9.09%,差异具有统计学意义(P<0.05)。观察组中高危组患者Hcy水平水平明显高于中危组,差异具有统计学意义(P<0.05)。结论同型半胱氨酸与高血压的发病有关,同型半胱氨酸升高,罹患高血压的几率升高,且发生心脑血管事件的几率也增高,且危险性越高。
Objective To analyze the relationship between homocysteine (Hcy) and Hypertension. Methods Sixty-six patients with Hypertension (Hcy> 10μmol / L) were selected as the observation group. Sixty-six healthy subjects (Hcy <10μmol / L) were selected as the control group. Plasma total homocysteine levels were measured by enzymatic cycling in both groups. Hcy levels and incidence of cardiovascular and cerebrovascular events were compared between the two groups, Hcy levels in different risk groups were compared. Results At admission, 1 and 3 months later, the Hcy level in the observation group was significantly higher than that in the control group (P <0.05). The incidence of cardiovascular and cerebrovascular events in the observation group was significantly higher than that in the control group (22.73%) In the control group, 9.09%, the difference was statistically significant (P <0.05). The level of Hcy in the high-risk group was significantly higher in the observation group than in the moderate-risk group (P <0.05). Conclusions Homocysteine is associated with the development of hypertension. Homocysteine is increased, the risk of developing hypertension is increased, and the risk of cardiovascular and cerebrovascular events is also increased, and the risk is higher.