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连续测定70例风湿性疾病患者PRL基础水平,并与40例健康者作对照。结果:32例SLE中9例高泌乳素血症,且血PRL与SLE活动指数相关。同时测定PRL和ANA表明,高泌乳素血症患者的ANA阳性率高。以上结果揭示PRL作为免疫调节激素在SLE发病中有一定作用。
70 cases of rheumatic diseases in patients with continuous determination of PRL basic level, and 40 healthy controls. Results: Nine of 32 patients with SLE had hyperprolactinemia, and the blood PRL correlated with SLE activity index. Simultaneous determination of PRL and ANA indicates that patients with hyperprolactinemia have a high ANA positive rate. The above results reveal that PRL plays a role in the pathogenesis of SLE as an immunomodulatory hormone.