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我院1987年8月至1989年11月共做肾移植手术228例次,其中有3例发生无菌性骨坏死,均为服用普通免疫抑制剂的患者,现报告如下。病例摘要例1:女患,43岁。诊断慢性肾盂肾炎。肾功能不全,尿毒症。於1986年4月行血液透析,每周两次,每次4～5小时,肝素用量为0.8～1mg/kg 体重。透析51次。同年10月21日行肾移植术。术中用琥珀酰氢化可的松(HCSS)300mg/d,氟美松60mg/d。术后予 HC-SS1500mg/d。进食后服用普通免疫抑制剂 Aza175mg/d,Pred90mg/d,半年后 Pred 改为35mg/d。实验室检
Our hospital from August 1987 to November 1989 a total of 228 cases of kidney transplants were done, of which 3 cases of osteonecrosis occurred in aseptic, are taking ordinary immunosuppressive patients, are as follows. Case Summary Example 1: female patient, 43 years old. Diagnosis of chronic pyelonephritis. Renal insufficiency, uremia. In April 1986 hemodialysis, twice a week, each 4 to 5 hours, the amount of heparin 0.8 ~ 1mg / kg body weight. Dialysis 51 times. October 21 the same year, kidney transplantation. Intraoperative succinyl hydrocortisone (HCSS) 300mg / d, dexamethasone 60mg / d. Postoperative HC-SS 1500mg / d. After taking the general immunosuppressive drugs Aza175mg / d, Pred90mg / d, six months after the Pred to 35mg / d. Laboratory test