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目的观察米索前列醇片用于剖宫产者预防产后出血的效果。方法选择有高危因素剖宫产者60例,随机分为观察组及对照组,观察组30例,胎儿娩出后宫体注射缩宫素20 U、台下缩宫素10 U壶入,术后立即肛门塞药米索前列醇片400μg。对照组30例,胎儿娩出后宫体注射缩宫素20 U,台下缩宫素10 U壶入。观察两组术后24h内出血量。结果观察组术后2 h平均出血量(200±56)ml,与对照组(300±50)ml比较,差异有统计学意义(P<0.01)。两组血压、血氧饱和度、心率的影响比较,差异无统计学意义(P>0.05)。结论在常规使用缩宫素的同时,采用术后肛门塞药米索前列醇片,预防剖宫产术后出血临床效果好,且用药方便、安全。
Objective To observe the effect of misoprostol tablets for prevention of postpartum hemorrhage in cesarean section. Methods Sixty patients with risk factors for cesarean section were randomly divided into observation group and control group. The observation group consisted of 30 cases. After the fetus was delivered, the uterus was injected with 20 U of oxytocin and 10 U of oxytocin under the table. Immediately after operation, Anal stuffing misoprostol tablets 400μg. The control group of 30 cases, the fetus was delivered after injection of oxytocin 20 U, under the table oxytocin 10 U pot into. The amount of bleeding within 24 hours after operation was observed. Results The mean amount of bleeding at 2 hours after operation in the observation group was (200 ± 56) ml, which was significantly different from that in the control group (300 ± 50) ml (P <0.01). There was no significant difference between the two groups in blood pressure, oxygen saturation and heart rate (P> 0.05). Conclusions In the routine use of oxytocin, anal sphingomyelin tablets after operation, to prevent bleeding after cesarean section clinical effect, and the medication convenient and safe.