辐射增敏研究动向

• 作 者: Stratford IJ
• 出 处: 国外医学(放射医学核医学分册)
• 发表日期: 1988年02期
• 关键词: 乏氧细胞 放射治疗 肿瘤病 杀伤率 照射剂量 亲电性 研究动向 辐射增敏剂 最大耐受剂量 氧供

一、辐射增敏研究现状目前在肿瘤的临床放射治疗中,如果采用正常组织可耐受的照射剂量进行治疗,肿瘤的平均治愈率仅40%,提高射线对肿瘤的杀伤率之关键,仍在于克服那些对射线敏感性较差的乏氧细胞。因此,如何克服乏氧细胞已成为这一研究领域中各国学者共同努力的目标。综合目前所采用的方法,主要有:①增加对肿瘤组织的氧供;②中子治疗;③

I. Current Status of Radiation Sensitization Research Currently, in the clinical radiotherapy of cancer, if the radiation dose that can be tolerated by normal tissues is used for treatment, the average cure rate of the tumor is only 40%, and the key to improving the kill rate of radiation against tumor is still Overcome those hypoxic cells that are less sensitive to radiation. Therefore, how to overcome hypoxic cells has become the goal of all scholars in this research field. The methods used in the current synthesis include: 1 increasing oxygen supply to tumor tissues; 2 neutron therapy; 3