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目的证实该制剂对胃炎的治疗作用。方法胃炎颗粒剂是民间治疗胃肠疾病的验方,经过剂型改革制成复方中药制剂。用该制剂对利血平和阿斯匹林诱发的大鼠进行了急性胃炎实验。结果胃炎冲剂对利血平诱发的大鼠急性胃炎实验,剂量在100、200、300 mg.kg-1的抑制率分别为56.96%、82.59%、和89.22%,与对照组比较有极显著差异(P<0.001)。对阿斯匹林诱发的急性胃炎实验,剂量在100、200、300 mg.kg-1的抑制率分别为44.20%、71.63%和90.85%,与对照组比较有极显著差异(P<0.001)。结论本品对由利血平和阿斯匹林诱发的大鼠急性胃炎均有较强的抑制作用。
Objective To confirm the therapeutic effect of this preparation on gastritis. Gastritis Granules is a prescription for the treatment of gastrointestinal diseases in the private sector and is made into a compound traditional Chinese medicine preparation after the reform of dosage form. Acute gastritis experiments were conducted with reserpine and aspirin-induced rats. Results The gastritis granules against reserpine-induced acute gastritis in rats, the dose of 100,200,300 mg.kg-1 inhibition rates were 56.96%, 82.59%, and 89.22%, compared with the control group were significantly different (P <0.001). Aspirin-induced acute gastritis experiment showed that the inhibition rates at aspirin-induced acute gastritis were 44.20%, 71.63% and 90.85% at 100, 200 and 300 mg.kg-1, respectively, which were significantly different from those of the control group . Conclusion This product has a strong inhibitory effect on rats with acute gastritis induced by reserpine and aspirin.