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目的:研究苦参在体内对免疫功能的作用。方法:小鼠口喂苦参溶液2周后检测脾细胞和胸腺细胞对ConA和LPS刺激的增殖反应,脾细胞产生白细胞介素2(IL-2),以及腹腔巨噬细胞产生白细胞介素1(IL-1)等指标。结果:口服苦参组上述三项指标均明显低于饮用自来水的对照组。结论:苦参在体内对免疫功能具有很明显的抑制作用。
Objective: To study the effect of Sophora flavescens on immune function in vivo. METHODS: After 2 weeks of oral administration of Sophora flavescens in mice, proliferative responses to splenocytes and thymocytes stimulated by ConA and LPS were measured. Interleukin-2 (IL-2) was produced in spleen cells and interleukin-1 was produced in peritoneal macrophages. (IL-1) and other indicators. RESULTS: The above three indicators of oral flavescens group were significantly lower than those of control group drinking tap water. Conclusion: Sophora flavescens has a significant inhibitory effect on immune function in vivo.