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在重症监护病房（ＩＣＵ）中１８９例伴有肺部感染的病人分成甲、乙两组，分别给予氨基糖苷类抗生素和第三代头孢菌素治疗，并在治疗前后随访其临床症状、体征、血白细胞计数、胸片和痰细菌学检查。发现甲组中硫酸妥布霉素和其他氨基糖苷类抗生素的临床有效率分别为８２．５％和６０．５％，前者细菌阴转率等均高于后者；乙组中头孢哌酮／舒巴坦和其他第三代头孢菌素临床有效率分别为８８．４％和７５．０％，前者细菌阴转率等均高于后者。结合实验结果对重症监护病房中的肺部感染病人，提议适当的治疗方案。
A total of 189 patients with lung infection in intensive care unit (ICU) were divided into A and B groups, treated with aminoglycoside antibiotics and third generation cephalosporins respectively. The clinical symptoms, signs, Blood white blood cell count, chest X-ray and sputum bacteriological examination. The clinical efficacies of tobramycin sulfate and other aminoglycoside antibiotics in group A were 82.5% and 60.5%, respectively. The former was higher than the latter in bacterial negative conversion rate. In group B, cefoperazone / Sulbactam and other third-generation cephalosporins clinically effective rates were 88.4% and 75.0%, the former bacterial negative conversion rate were higher than the latter. Combined with the experimental results of patients with pulmonary infection in intensive care unit, the proposed appropriate treatment.