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目的 探讨儿童食管炎的发病、临床特征及其诊断治疗。方法 对 12 5例食管炎患儿的内镜表现、临床特征和幽门螺杆菌 (H .pylori)感染情况进行分析。 结果 4 0 32例胃镜检查病例中 ,诊断为食管炎者 12 5例(3 1% )。H .pylori阳性总例数 74 5 ,阳性率 18 5 % (74 5 / 4 0 32 ) ,其中非食管炎者阳性 72 1例 ,阳性率 18 5 %(72 1/ 390 7) ,食管炎者阳性 2 4例 ,阳性率 19 2 % (2 4 / 12 5 ) ,两者阳性率差异无显著性 (P >0 0 5 )。食管炎临床表现呕吐 5 5 2 % (6 9/ 12 5 ) ,胸痛 2 0 8% (2 6 / 12 5 ) ,嗳气 2 2 4 % (2 8/ 12 5 ) ,不同年龄组三种症状比较差异有显著性(P <0 0 5 ) ;腹痛 4 4 0 % (5 5 / 12 5 ) ,咽部不适 14 4 % (18/ 12 5 ) ,不同年龄二种症状比较差异无显著性 (P >0 0 5 )。内镜下病变全部局限食管下段 ,表现为充血、糜烂和渗出 ,未见溃疡、狭窄和局部组织及食管下段毛细血管增生 ,未检出食管裂孔疝 ;Ⅰ级 116例 ,占 92 8% (116 / 12 5 ) ,Ⅱ级 8例 ,占 6 4 % (8/ 12 5 ) ,Ⅲ级 1例 ,占 0 8%(1/ 12 5 ) ,各年龄组分级差异无显著性 (P >0 0 5 )。结论 广州地区儿童上消化道疾病H .pylori检出率为18 5 % ,食管炎患儿H .pylori感染与其他上消化道疾病相近 ;儿童食管炎占上?
Objective To investigate the incidence, clinical features and diagnosis and treatment of children with esophagitis. Methods Endoscopic findings, clinical features and H. pylori infection in 125 children with esophagitis were analyzed. Results Among 40 32 gastroscopy cases, 125 (31%) were diagnosed as esophagitis. The total number of H.pylori positive cases was 74.5, with a positive rate of 18.5% (74 5/40). The positive rate of non-esophagitis was 72 1, the positive rate was 18 5% (72 1/390 7), esophagitis There were 24 positive cases and the positive rate was 19 2% (2 4/125). There was no significant difference between them (P> 0.05). The clinical manifestations of esophagitis were 55.2% (69/25), 29.0% (26/25) of chest pain, 22.4% (28/25) of asthma, and the difference of three symptoms among different age groups The difference was significant (P <0.05); abdominal pain was 44.0% (5/125) and pharyngeal discomfort was 14.4% (18/125), there was no significant difference between the two groups > 0 0 5). Endoscopic lesion all the limitations of the lower esophagus, showed congestion, erosion and exudation, no ulcers, stenosis and local tissue and lower esophageal capillary proliferation, did not detect hiatal hernia; 116 cases of grade I, accounting for 92.8% ( (P <0.05). There were 8 cases in grade Ⅱ, 8 cases in grade Ⅱ, 8 cases in grade Ⅲ, 1 case in grade Ⅲ, accounting for 08% (1/12) 0 5). Conclusions The prevalence of H.pylori in children with upper gastrointestinal tract disease in Guangzhou is 18.5%. H.pylori infection in children with esophagitis is similar to other upper gastrointestinal diseases.