The codon-optimized capsid gene of duck circovirus can be highly expressed in yeast and self-assembl

• 作 者: YANG Cui XU Yu JIA Ren-yong LI
• 机 构: AvianDiseaseResearchCentre,InstituteofPreventiveVeterinaryMedicine,KeyLaboratoryofAnimalDiseaseandHu
• 出 处: 农业科学学报：英文版
• 发表日期: 2017年7期
• 关键词: 毕赤酵母表达系统 衣壳蛋白基因 病毒样颗粒 密码子优化 圆环病毒 自组装 CAP蛋白 多克隆抗体 capsid gene codon＇optimization
• 基金项目: This study was supported by the National Science and Technology Support Program （2015BAD12B05）, the China Agricultural Research System （CARS-43-8）, the Integration and Demonstration of Key Technologie

The capsid(Cap) protein, which is the only structural protein of duck circovirus(DuCV), is the most important antigen for the development of vaccines against DuCV and the virus' s serological diagnostic methods. In order to use yeast expression system