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目的探讨氨茶碱治疗小儿哮喘的安全有效方法。方法 52例小儿哮喘患者随分为对照组26例,治疗组26例。对照组给予茶碱每次4～5mg/kg,每6h1次。治疗组采用持续静滴方法:首次剂量按5-6mg/kg,20-30分钟快速静滴,维持量按0.8mg/(kg.h)持续静滴。对超过标准体重、肥胖者,以同龄标准体重计算。对比观察两组疗效,着重观察了两组患儿哮喘症状缓时间。结果两组对比有显著性差异(P<0·01),且对照组所致不良反应较多,治疗组不良反应少且疗效明显。结论治疗组安全有效,此疗法值得推广。
Objective To investigate the safe and effective method of aminophylline treatment of pediatric asthma. Methods 52 pediatric asthma patients were divided into control group (n = 26) and treatment group (n = 26). The control group was given theophylline every 4 ~ 5mg / kg every 6h1 times. The treatment group continued infusion method: the first dose by 5-6mg / kg, 20-30 minutes rapid intravenous infusion, maintenance dose 0.8mg / (kg.h) sustained intravenous infusion. For more than standard weight, obese, with the same age standard weight calculation. The curative effect of the two groups were compared, and the asthmatic symptom relief time was observed in both groups. Results There was significant difference between the two groups (P <0.01), and the control group caused more adverse reactions, the treatment group had fewer adverse reactions and the curative effect was obvious. Conclusion The treatment group is safe and effective, which is worth promoting.