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目的:探讨老年食管癌患者发生术后肺部并发症(PPC)的危险因素。方法:对我院2009年3月至2012年06月282例行食管癌根治术患者的临床资料进行回顾性分析,收集其术前、术中及术后相关资料与数据,统计各种PPC,进行Logistic回归分析。结果:患者PPC的发生率为26.2%(74/282),单因素Logistic回归分析筛选22个相关因素;多因素分析显示,年龄(OR=1.485)、吸烟(OR=1.546)、ASA评级(OR=2.258)、术前存在肺部疾病(OR=1.383)、术中气管插管时间(OR=1.210)、术后机械通气时间(OR=1.302)为发生PPC的独立危险因素。结论:高龄、大量吸烟、ASA高评级、术前伴存肺部疾病、长时间气管插管及机械通气使老年食管癌患者易发生PPC。
Objective: To investigate the risk factors of postoperative pulmonary complications (PPC) in elderly patients with esophageal cancer. Methods: The clinical data of 282 patients undergoing esophagectomy for radical resection from March 2009 to June 2012 in our hospital were retrospectively analyzed. The data of preoperative, intraoperative and postoperative related data and data were collected, and various types of PPC, Logistic regression analysis. Results: The incidence of PPC in patients was 26.2% (74/282). Single factor Logistic regression analysis screened 22 related factors. Multivariate analysis showed that age (OR = 1.485), smoking (OR = 1.546), ASA = 2.258). Pulmonary disease preoperatively (OR = 1.383), intubation time (OR = 1.210) and postoperative mechanical ventilation time (OR = 1.302) were independent risk factors for PPC. Conclusion: Elderly patients, large number of smoking, high ASA grade, preoperative pulmonary disease, prolonged tracheal intubation and mechanical ventilation make elderly patients with esophageal cancer prone to PPC.