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N-亚硝基化合物包括亚硝胺及亚硝酰胺,是一种强烈的致癌剂。在已实验过的多种动物中,至今未发现任何一种动物能耐受而不发癌。目前虽尚未能证明人类癌症与N-亚硝基化合物或其前体有关,但大量的动物实验及流行病学调查提示:这类化合物特别是其体内合成在人类鼻咽癌、食道癌及胃癌的发生上可能具有重要作用。仅就目前对外环境中的N-亚硝基化合物的研究资料看来,水、空气、土壤及一般食品中的含量均较低。值得重视的是硝
N-nitroso compounds including nitrosamines and nitrosamides, is a strong carcinogen. Of the many animals that have been tested, no animal has been found tolerant to cancer. At present, although it has not been proved that human cancer is related to N-nitroso compounds or their precursors, a large number of animal experiments and epidemiological investigations suggest that such compounds, especially their in vivo synthesis, are highly effective in human nasopharyngeal carcinoma, esophageal cancer and The occurrence of gastric cancer may have an important role. Only the current study of N-nitroso compounds in the external environment seems to contain low levels of water, air, soil and food in general. It is worth noting that nitrate