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炎症是指机体对微生物感染、异体物质或其他体内产物如抗原抗体复合物所致损伤的一种反应。炎症的病理生理作用是局限和消除损伤因子,进行组织修复,但长期反复的炎症可导致一系列的疾病。血糖升高则是患者对于应激的正常生理反应,在机体受到严重创伤、出现脑血管意外、急性心肌梗死、感染性休克等强烈刺激时,它可满足葡萄糖依赖器官的能量需要,但是长期的高糖状态易使机体出现一系列神经内分泌功能紊乱,破坏原有生理状态下的平衡。研究表明,高糖状态对感染的机体有较强的促炎作用,可使机体炎性介质增加,影响炎症的发生、发展过程及其预后[1]。笔者就高糖促进组织炎症的分子机制,以及对炎症预
Inflammation refers to the body’s response to microbial infections, allogeneic substances, or damage caused by other in vivo products, such as antigen-antibody complexes. The pathophysiological role of inflammation is to limit and eliminate damage factors for tissue repair, but long-term repeated inflammation can lead to a series of diseases. Hyperglycemia is the patient’s normal physiological response to stress, which can meet the energy needs of glucose-dependent organs in the body when subjected to severe trauma, cerebrovascular accident, acute myocardial infarction, septic shock and the like, but long-term High sugar state easy to make the body appear a series of neuroendocrine disorders, undermining the original physiological balance. Studies have shown that high sugar status on the infected body has a strong pro-inflammatory effect, can increase the body’s inflammatory mediators, affecting the occurrence of inflammation, development and prognosis [1]. The author on high glucose promote the molecular mechanism of tissue inflammation, as well as pre-inflammatory