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目的了解宁夏HIV感染者合并梅毒感染的分布特征及其影响因素。方法对宁夏籍确证的HIV感染者血清采用ELISA方法与TRUST方法联合检测梅毒抗体,对合并感染样本的信息进行线性趋势χ~2检验及Logistic回归分析。结果 2002年-2014年,各年合并感染患者数随年份逐年增加。2014年合并感染率已达到当年确证HIV感染者人数的32.18%。经线性趋势χ~2检验,合并感染阳性数与年份间存在线性趋势(P<0.01)。且合并感染患者在宁夏各市均有分布,银川市所占比例最高(53.97%)。多因素Logistic回归分析结果显示,仅感染途径为是否合并感染的影响因素,同性传播为危险因素。结论男男性行为人群是HIV合并梅毒感染的高危人群,有针对性地开展特定人群的行为干预是做好HIV/梅毒合并感染预防控制的有效途径。
Objective To understand the distribution and influencing factors of syphilis infection in Ningxia HIV infected persons. Methods The syphilis antibody was detected by ELISA and TRUST in HIV-positive sera of confirmed HIV-positive patients in Ningxia. The linear trend χ ~ 2 test and Logistic regression analysis were performed on the information of the infected patients. Results From 2002 to 2014, the number of patients with concurrent infections increased year by year with the year. In 2014, the combined infection rate reached 32.18% of the confirmed HIV-infected persons in that year. The linear trend χ ~ 2 test, there was a linear trend between the positive number of co-infection and the year (P <0.01). The patients with co-infection were distributed in all cities of Ningxia, Yinchuan accounted for the highest proportion (53.97%). Multivariate Logistic regression analysis showed that the only way of infection was whether the infection of the factors, same-sex transmission as a risk factor. Conclusions MSM is a high risk population of HIV infection with syphilis. Targeted intervention in specific population is an effective way to prevent and control HIV / syphilis infection.