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在大鼠出生后的第八至十天,子宫上皮细胞形成了“核体”,这种结构可能反映子宫发育某一个关键阶段染色质的改变。在大鼠出生后的第七至九天给予孕酮减少“核体”的形成并完全抑制在3周大鼠创伤子宫引起的蜕膜瘤的形成。在7～9天给予乙菧雌酚可增加“核体”的数量,对蜕膜反应无作用或有易化作用。在本工作中作者希望了解孕酮对蜕膜形成的抑制作用是暂时的或是持久的。实验分四组进行。第一组注射芝麻油做为对照组。第二、三、四组分别于出生后3～5天,7～
On the eighth to tenth day after birth, uterine epithelial cells form “nuclei”, a structure that may reflect chromatin changes at a critical stage of uterine development. Progesterone was administered to reduce the formation of “nucleosomes” on days seven to nine after birth in rats and completely inhibit the formation of decidual tumors in the wounded uterus of rats at 3 weeks. In 7 to 9 days to give diethylstilbestrol can increase the number of “nucleosomes”, no effect on the decidua reaction or facilitation. In this work, the authors wish to understand that the inhibitory effect of progesterone on decidual formation is temporary or permanent. The experiment was divided into four groups. The first group injected sesame oil as a control group. The second, third and fourth groups were born 3 to 5 days after birth, 7 ~