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近十年来世界医学文献中愈来愈多地报导硅肺并发胶原病的病例。硅肺—关节炎或硅肺并发类风显性关节炎的病例在目前的文献中已超过100例,硅肺并发硬皮症的病例已有15例之多;同样还见到硅肺并发结节性动脉外膜炎等。通过组织化学的、免疫学的、病理形态学的研究和对硅肺并发胶原病病例的观察,目前大多数学者把硅肺看作是由于机体反应性改变发展成的全身性疾患,同时在它的发病机制中发现有某些共同性(自体致敏作用和免疫过程破坏)而认为与胶原病相
In the last decade, more and more cases of silicosis complicated by collagen disease have been reported in the world medical literature. More than 100 cases of silico-arthritis or silico-silicotic rheumatoid arthritis have been documented in the current literature, with as many as 15 cases of silicosis and scleroderma; Arterial adventuritis and so on. By histochemical, immunological, pathomorphological studies and the observation of cases of silicosis complicated with collagen disease, most scholars at present consider the silicosis as a systemic disorder developed due to the body’s reactive changes, Found in the pathogenesis of some common (self-sensitization and immune damage) and that collagen phase