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目的观察联用果糖和参麦注射液治疗慢性阻塞性肺疾病(COPD)急性加重期合并心肌损害的疗效。方法将63例COPD急性加重期合并心肌损害病人随机分为两组,对照组采用常规治疗,观察组在对照组的基础上联用丹参、果糖和参麦注射液治疗,比较两组症状、体征、心电图和心肌酶学恢复时间。结果观察组主要症状、体征的改善时间及心率、心电图、心肌酶的恢复时间均较对照组显著缩短(P<0.01)。观察组总有效率80.0%,显效率为53.3%,均明显高于对照组的54.5%、21.2%(P<0.01)。结论联用果糖和参麦注射液对急性加重期COPD合并心肌损害病人疗效满意。
Objective To observe the curative effect of combining fructose and shenmai injection on patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) complicated with myocardial damage. Methods Sixty-three patients with acute exacerbation of COPD and myocardial damage were randomly divided into two groups. The control group was treated with conventional therapy. The observation group was treated with Salvia miltiorrhiza, fructose and Shenmai injection on the basis of the control group. The symptoms and signs , Electrocardiogram and myocardial enzymology recovery time. Results The main symptoms and signs of improvement time and heart rate, electrocardiogram and myocardial enzyme recovery time of the observation group were significantly shorter than those of the control group (P <0.01). The total effective rate in the observation group was 80.0%, the effective rate was 53.3%, which was significantly higher than that in the control group (54.5%, 21.2%, P <0.01). Conclusions Combination of fructose and Shenmai injection is effective in patients with acute exacerbation of COPD and myocardial damage.