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该文应用自动图像分析仪对３５例肝穿刺或手术标本的细胞核ＤＮＡ倍体型及其与声像图之间的关系进行分析。结果表明：异倍体（ＡＮ）发生率在正常组或其余各组间有高度显著性差异（Ｐ＜０．０１）；大肝癌组与小肝癌组间有显著性差异（Ｐ＜０．０５）；但弥漫性肝癌组与小肝癌组及大肝癌组间无显著性差异（Ｐ＞０．０５）。肿瘤的异倍体细胞数在无包膜组、高回声组与有包膜组、低回声组之间有高度显著性差异（Ｐ＜０．０１）；在有癌栓组与小肝癌组之间有显著性差异（Ｐ＜０．０５）；与大肝癌组之间无显著性差异。晕环、后方回声衰减的有无与异倍体细胞数无显著相关（Ｐ＞０．０５）。提示肿块大于３ｃｍ、无包膜、高回声、有癌栓是肿瘤恶性程度较高的超声表现，具有预后诊断价值。
In this paper, an automatic image analyzer was used to analyze the nuclear DNA ploidy in 35 liver biopsies or surgical specimens and their relationship with sonography. The results showed that the incidence of aneuploidy (AN) was significantly different between the normal group or the other groups (P<0.01); there was a significant difference between the large hepatocellular carcinoma group and the small hepatocellular carcinoma group (P<0.05). However, there was no significant difference between the diffuse liver cancer group and the small hepatocellular carcinoma group and the large hepatocellular carcinoma group (P>0.05). The number of aneuploid cells in the tumor was significantly different between the non-enveloped group, the hyperechoic group and the encapsulated group, and the hypoechoic group (P<0.01); There was a significant difference between the two groups (P<0.05); there was no significant difference between the group and the large HCC group. The presence of halo and posterior echo attenuation was not significantly associated with the number of aneuploid cells (P>0.05). It suggests that the tumor is larger than 3cm, no capsule, hyperechoic, and tumor thrombus are the sonographic manifestations of high degree of malignancy and have prognostic value.