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颈上交感神经节（ SCG）是交感神经系统的重要组成部分，作为颈部最大的神经节，与颈椎毗邻关系密切。颈椎紊乱可刺激SCG并影响内分泌及免疫功能，是引起颈源性疾病的原因之一。目前众多研究证实SCG可通过神经纤维及神经活性物质与内分泌和免疫系统广泛联系，并参与神经－内分泌－免疫调控。但目前对SCG与免疫和内分泌系统研究缺乏从宏观角度整体的联系，制约了对发病机制的探索，有待更加深入的研究。“,”Superior sympathetic ganglion(SCG) is an important part of the sympathetic nervous system, as the largest ganglion of the neck,it is closely adjacent to and associated with the cervical spine.Cervical spine disorders can stimulate SCG and affect the endocrine and immune function ,which is a cause of cervical vertebra disease.At present many studies have confirmed that SCG can widely contact with the endocrine and immune system through the nerve fibers and neural active substance,and participate in the neuro-endocrine-immune regulation.However the current research on SCG and immune system and endocrine system is lack of overall connection from the macroscopic angle, which has restricted the exploration of the mechanism and needs further studies.