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目的 :研究妊娠急性胰腺炎 (AP)发生的相关因素和住院的流行病学情况。方法 :回顾近 1 2年住本院的妊娠AP病例 ,并以同期在本院终止妊娠者为对照 ,分析妊娠AP的特点。结果 :妊娠AP 1 7例 ,占在本院终止妊娠者的 0 0 4 % ,或占住本院结束其中晚期妊娠者的 0 1 1 %。AP者死胎流产、母亲死亡、双胎、妊娠急性脂肪肝的比例均高于无AP妊娠者 (P <0 0 5)。AP者胆系疾病比例、平均ALT、AST、LDH、Ch、甘油三酯、CK、α 羟丁酸脱氢酶均高于对照组 (P <0 0 5～P <0 0 0 1 )且高于正常标准。结论 :妊娠期AP的病因与胆石症、高脂血症、急性脂肪肝有关 ,并可能与双胎有关 ;妊娠期重症AP对孕妇及胎儿的生存有极大威胁
Objective: To study the related factors of acute pregnancy pancreatitis (AP) and the epidemiology of hospitalization. Methods: To review the cases of pregnancy AP in our hospital in the past 12 years and to compare the characteristics of pregnancy AP with the termination of pregnancy in our hospital in the same period. Results: Seventeen APs were found in pregnancy, accounting for 0.4% of all pregnancies in our hospital or 0.1% of those in late pregnancy at the end of hospital. AP stillbirth abortion, maternal deaths, twins, acute fatty liver pregnancy were higher than those without AP pregnancy (P <0 05). The percentage of biliary diseases in AP group was higher than that in control group (P <0.05 ~ P <0.01) and the average ALT, AST, LDH, Ch, triglyceride, CK and α-hydroxybutyrate dehydrogenase In the normal standard. Conclusion: The etiology of AP in pregnancy is related to cholelithiasis, hyperlipidemia and acute fatty liver, and may be related to twins. Severe AP in pregnancy has a great threat to the survival of pregnant women and fetuses