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抽动——秽语综合征(tourette’s syndrome, TS)是儿童常见的神经系统疾病之一,临床表现以多发性运动肌不自主抽动伴有不自主发声为特征。本文报告12例TS患者,经氟哌啶醇或/和泰必利(tiapride)治疗无效或因副反应大不能耐受,采用肌苷治疗,取得满意疗效。 资料与方法 男9例,女3例:年龄4～16岁,平均7.3岁。病程2月～8年,平均6.4月。临床表现均符合《中国精神疾病分类方案与诊断标准》1989年第二版Tourette综合征诊断标准。患者具有反复发作性面部、颈
Tourette’s syndrome (TS) is one of the most common neurological diseases in children. Its clinical manifestations are characterized by involuntary twitching of multiple motor muscles accompanied by involuntary vocalizations. This article reports 12 cases of TS patients, the haloperidol or / and tiapride (tiapride) treatment is invalid or because of side effects can not tolerate, with inosine treatment, and achieved satisfactory results. Materials and Methods 9 males and 3 females: aged 4 to 16 years, mean 7.3 years old. Duration of 2 months to 8 years, an average of 6.4 months. Clinical manifestations are in line with “China’s mental illness classification scheme and diagnostic criteria” second edition of 1989 Tourette syndrome diagnostic criteria. Patients have recurrent facial, neck