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[目的]拓展对Merkel细胞癌(Merkel cell carcinoma,MCC)这一极其罕见神经内分泌瘤的认识。[方法]报道一例发于右眼睑的Merkel细胞癌,并对其流行病学、病因、病理、诊断、临床分期治疗等进行文献复习。[结果]Merkel细胞癌是一种好于皮肤的少见的恶性肿瘤,该病预后较差,易局部复发及转移。在高度紫外线暴露地区较常见,且和免疫抑制相关。Merkel细胞癌的诊断以病理诊断为金标准。目前Merkel细胞癌尚无成熟的治疗方案,但首选手术,术后辅助。[结论]如果出现眼睑包块,并有病理学和免疫抑制的证据表明是神经内分泌瘤,很有必要考虑是Merkel细胞瘤。
[Objective] To develop an understanding of the extremely rare neuroendocrine tumor of Merkel cell carcinoma (MCC). [Method] A case of Merkel cell carcinoma, which was made in the right eyelid, was reported. The epidemiology, etiology, pathology, diagnosis and clinical staging were reviewed. [Result] Merkel cell carcinoma is a rare malignant tumor which is better than skin. The disease has poor prognosis and easily local recurrence and metastasis. It is more common in areas of high UV exposure and is associated with immunosuppression. Merkel cell carcinoma of the diagnosis of pathological diagnosis as the gold standard. Merkel cell carcinoma is currently no mature treatment options, but the preferred surgery, postoperative assistance. [Conclusions] Merkel’s tumor is considered essential if there are masses of the eyelid and pathological and immunosuppressive evidence of neuroendocrine tumors.