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目的观察肺炎支原体肺炎患儿全血锌、铁、铜、钙、镁等微量元素含量的变化,并探讨其在肺炎支原体肺炎发病机制中的意义。方法采用微分电位溶出测定法检测43例肺炎支原体肺炎患儿和40例正常对照组儿童全血锌、铁、铜、钙、镁等微量元素含量。结果肺炎支原体肺炎患儿组锌和铁含量较正常对照组低,两组间差异有统计学意义(P<0.05);而铜、钙、镁两组间无统计学差别(P>0.05)。结论肺炎支原体肺炎患儿锌、铁含量缺乏,这可能是造成患儿免疫功能减低、免疫调节功能紊乱的重要原因。
Objective To investigate the changes of trace elements such as zinc, iron, copper, calcium and magnesium in whole blood of children with Mycoplasma pneumoniae pneumonia and to explore its significance in the pathogenesis of Mycoplasma pneumoniae pneumonia. Methods The contents of zinc, iron, copper, calcium, magnesium and other trace elements in whole blood of 43 children with Mycoplasma pneumoniae pneumonia and 40 normal controls were detected by differential potentiometric dissolution assay. Results The levels of zinc and iron in children with Mycoplasma pneumoniae pneumonia were lower than those in the control group. There was significant difference between the two groups (P <0.05). There was no significant difference between the two groups (P> 0.05). Conclusions Children with Mycoplasma pneumoniae pneumonia lack of zinc and iron content, which may be caused by immune dysfunction in children, immune dysregulation of the important reasons.