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急性缺血性中风是一种常见而严重的老年性疾病。其治疗目标应是挽救可逆性缺血组织—缺血性半暗带(IP) ,以缩小梗塞范围和改善神经功能。在实验性中风和临床实践中 ,有必要区分可逆和不可逆的缺血损害 ,影像技术和生化标志可为此提供线索。可逆不可逆损害演变的可能机制有诸多方面 ,且不同个体均具有差异。应根据不同个体的状况以及对 IP的深入认识 ,确定较佳的治疗策略。
Acute ischemic stroke is a common and serious old-fashioned disease. Its goal of treatment should be to save the reversible ischemic tissue - ischemic penumbra (IP), to reduce infarct size and improve neurological function. In experimental stroke and clinical practice, it is necessary to distinguish between reversible and irreversible ischemic insult, and imaging techniques and biochemical markers may provide clues to this. There are many possible mechanisms for the reversible irreversible damage evolution, and different individuals have differences. Should be based on the status of different individuals as well as in-depth understanding of IP to determine a better treatment strategy.