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采用免疫过氧化物酶技术和单克隆抗体研究感染和非感染耳的耳道皮肤、鼓膜、胆脂瘤上皮及中耳和鼓窦肉芽组织等活检标本的淋巴细胞亚型,并探索其在不同类型中耳炎中的意义。包括辅助/诱导性 T 细胞(Th/i)、抑制/细胞毒性 T 细胞(Ts/c)的比率,自然杀伤细胞(NK)及 B 细胞的百分数。结果认为非感染外耳道皮肤、鼓膜和胆脂瘤膜淋巴细胞少,无特征性炎性反应;感染的外耳道皮肤、鼓膜、胆脂瘤膜和乳突手术后腔内皮肤的 Th/i 减少,淋巴细胞亚型比率始终较低,是长期慢性感染
Immunoperoxidase technique and monoclonal antibody were used to study lymphocyte subsets in the biopsy specimens of infected and non-infected ear canal, tympanic membrane, cholesteatoma epithelium and middle ear, The significance of type otitis media. Including the ratio of helper / inducible T cells (Th / i), inhibition / cytotoxic T cells (Ts / c), the percentage of natural killer cells (NK) and B cells. The results showed that non-infected external auditory canal skin, tympanic membrane and cholesteatoma membrane lymphocyte less, no characteristic inflammatory reaction; infected external auditory canal skin, tympanic membrane, cholesteatoma membrane and mastoid cavity after surgery to reduce Th / i, lymph The proportion of cell subtypes is always low, is a chronic chronic infection