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用免疫组化光镜和电镜技术对大鼠视前区β－内啡肽能神经纤维进行研究，结果显示：（１）内侧视前区β－内啡肽能神经纤维密度为（３．６３±０．２２）μｍ／１００μｍ２，外侧视前区为（１．７４±０．２１）μｍ／１００２μｍ２，两者差别有显著性（Ｐ＜０．０１）；（２）在视前区，阳性纤维见于无髓纤维。阳性轴突与免疫反应阴性终末之间形成轴－棘或轴－树突触，突触前、后膜比较对称。从形态学上提示β－内啡肽在视前区的功能部位为内侧视前区，β－内啡肽的抑制功能与其突触类型有关。
By means of immunohistochemistry and electron microscopy, the β-endorphin nerve fibers in the preoptic area of rats were studied. The results showed that: (1) The density of β-endorphin nerve fibers in the preoptic area was (3.63 ± 0.22) μm / 100μm2, and the preoptic area was (1.74 ± 0.21) μm / 1002μm2 (P <0.01). (2) In the preoptic area, the positive Fibers found in non-myelinated fibers. Positive axons and immunoreactive negative terminal between the formation of axis - spine or axis - dendritic synapses, presynaptic and posterior membrane more symmetrical. Morphologically, it is suggested that the functional site of β-endorphin in the preoptic area is the medial preoptic area, and the inhibitory function of β-endorphin is related to its synaptic type.