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肠炎沙门菌(Salmonella enteritidis,SE)是一种特殊的泛嗜性胞内病原菌,也是最为常见的食物源性病原菌之一,通过污染鸡蛋进行传播。肠炎沙门菌能导致成年鸡隐性感染且长期排菌,容易为生产所忽视;并且能在污染的鸡蛋中增殖,却不会引起蛋内结构明显的变化。肠炎沙门菌病不但对禽类生产造成的经济损失无法估量,而且对人类的身体健康也造成很严重的危害。宿主的遗传背景对肠炎沙门菌病的抗性有着深远的影响,探索抗性相关基因的遗传特性和差异表达规律是研究鸡对肠炎沙门菌病抗性的必要途径。本文对鸡肠炎沙门菌病的致病机理和抗性相关基因的研究进展进行了阐述,以期为鸡抗病育种研究提供借鉴。
Salmonella enteritidis (SE) is a special pan-tropic intracellular pathogen and one of the most common food-borne pathogens that spread through contaminated eggs. Salmonella enteritidis can cause recessive infection in adult chickens and long-term bacteriostasis, easily overlooked by production, and can proliferate in contaminated eggs without causing significant changes in the structure of the egg. Salmonella enteritidis not only can not estimate the economic loss caused by bird production, but also causes serious harm to human health. The genetic background of the host has a profound impact on the resistance of Salmonella enteritidis. To explore the genetic characteristics and differential expression of resistance-related genes is a necessary way to study the resistance of Salmonella enteritidis to chickens. In this paper, the pathogenic mechanism of Salmonella enteritidis pathogenesis and resistance-related genes in the research are described in order to provide a reference for the study of chicken disease resistance breeding.