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目的探讨胃肠道恶性肿瘤的发生与雄激素受体的关系．方法应用放射配体结合分析法（ＲＢＡ）检测胃肠道恶性肿瘤患者及对照组外周血白细胞雄激素受体（ＡＲ），应用放射免疫测定试剂盒测定血浆中睾酮（Ｔ）浓度．受检对象为胃癌１０例，结肠癌１２例，直肠癌１２例．结果外周血白细胞ＡＲ含量：胃癌男性为４３０ｓｉｔｅｓ／ｃｅｌ±１０８ｓｉｔｅｓ／ｃｅｌ，女性为３６１ｓｉｔｅｓ／ｃｅｌ±４２ｓｉｔｅｓ／ｃｅｌ；结肠癌男性为３８８ｓｉｔｅｓ／ｃｅｌ±６８ｓｉｔｅｓ／ｃｅｌ，女性为３８２ｓｉｔｅｓ／ｃｅｌ±８３ｓｉｔｅｓ／ｃｅｌ；直肠癌男性为３８３ｓｉｔｅｓ／ｃｅｌ±１８ｓｉｔｅｓ／ｃｅｌ，女性为３３８ｓｉｔｅｓ／ｃｅｌ±２３ｓｉｔｅｓ／ｃｅｌ．所有胃肠道恶性肿瘤患者外周血白细胞ＡＲ含量明显低于对照组（男性为６１２ｓｉｔｅｓ／ｃｅｌ±５４ｓｉｔｅｓ／ｃｅｌ，女性为５８４ｓｉｔｅｓ／ｃｅｌ±４２ｓｉｔｅｓ／ｃｅｌ，Ｐ＜００１）；血浆中雄激素水平，胃癌男性与女性分别为２９２１ｎｇ／Ｌ±１１４９ｎｇ／Ｌ，３５５ｎｇ／Ｌ±１１３ｎｇ／Ｌ；结肠癌男性与女性分别为１１５２ｎｇ／Ｌ±６８ｎｇ／Ｌ，２５７ｎｇ／Ｌ±１４３ｎｇ／Ｌ；直肠癌男性与女性分别?
3. Objective To investigate the relationship between the occurrence of gastrointestinal malignancy and androgen receptor. Methods Radioligand binding assay (RBA) was used to detect peripheral blood leukocyte androgen receptor (AR) in patients with gastrointestinal cancer and control group. Plasma radioimmunoassay kit was used to determine the concentration of testosterone (T) in plasma. The subjects were 10 cases of gastric cancer, 12 cases of colon cancer, and 12 cases of rectal cancer. Results The peripheral blood leukocyte AR content was 430sites/cel±108sites/cel for gastric cancer and 361sites/cel±42sites/cel for females, 388sites/cel±68sites/cel for colon cancer, and 382sites/cel±83sites/cel for females. The rectal cancer males were 383 sites/cel±18 sites/cel, and the females were 338 sites/cel±23 sites/cel. The peripheral blood leukocyte AR content in all patients with gastrointestinal malignancy was significantly lower than that in the control group (612 sites/cel±54 sites/cel in males and 584 sites/cel±42 sites/cel in females, P<0.01); androgen levels in plasma The rates of males and females in gastric cancer were 2921 ng/L±1149 ng/L and 355 ng/L±113 ng/L, respectively; the colon cancer men and women were 1152 ng/L±68 ng/L and 257 ng/L±143 ng/L, respectively; Female separate?