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作者检测了106例恶性血液病血清腺苷脱氨酶活性。结果显示白血病、恶性淋巴瘤、多发性骨髓瘤、骨髓增生异常综合征和恶性组织细胞病的血清腺苷脱氨酶活性均较健康正常人明显增高,腺苷脱氨酶活性与体内瘤细胞负荷有一定关系,并随病情的缓解而下降。提示动态测定血清腺苷脱氨酶活性可作为恶性血液病病情监测和预后判断的一个指标。
The authors detected serum adenosine deaminase activity in 106 patients with hematologic malignancies. The results showed that serum adenosine deaminase activity in leukemia, malignant lymphoma, multiple myeloma, myelodysplastic syndrome, and malignant histiocytosis was significantly higher than that in healthy individuals, adenosine deaminase activity, and tumor cell load in vivo. There is a certain relationship, and it decreases with the relief of the disease. The dynamic measurement of serum adenosine deaminase activity can be used as an indicator of the condition monitoring and prognosis of hematological malignancies.