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目的观察甘精胰岛素联合瑞格列奈对老年2型糖尿病患者血糖的影响。方法对本院2010年3月至2012年8月期间采用甘精胰岛素联合瑞格列奈(观察组,n=50)和诺和灵30R(对照组,n=50)治疗的100例老年2型糖尿病患者的临床资料进行回顾性分析。结果观察组患者的空腹血糖(FPG)、早餐后2 h血糖(2hPG)、糖化血红蛋白(HbA1c)、胰岛素用量、体重指数(BMI)和低血糖事件发生都明显改善,显著地优于对照组,并且观察组的疗效明显优于对照组。结论甘精胰岛素联合瑞格列奈能较好地控制老年2型糖尿患者的血糖,并且低血糖发生率低,疗效好,是治疗老年2型糖尿病的理想方案,值得临床推广应用。
Objective To observe the effect of insulin glargine combined with repaglinide on blood glucose in elderly type 2 diabetic patients. Methods A total of 100 elderly 2 patients treated with glargine and repaglinide (observation group, n = 50) and Novolin 30R (control group, n = 50) between March 2010 and August 2012 in our hospital The clinical data of diabetic patients were retrospectively analyzed. Results The fasting blood glucose (FPG), 2hPG, HbA1c, insulin, body mass index (BMI) and incidence of hypoglycaemia in observation group were significantly higher than those in control group, And the observation group was significantly better than the control group. Conclusion Glargine and repaglinide can effectively control the blood sugar of elderly patients with type 2 diabetes mellitus, and the incidence of hypoglycemia is low and the curative effect is good. It is an ideal treatment for type 2 diabetes mellitus in elderly. It is worthy of clinical application.