论文部分内容阅读
26例运动神经无病(MND)患者血清中IgM-神经节苷脂GM_1抗体检测的阳性率为65％,明显高于其他神经疾病(OND)组11％及正常人(NC)组。抗体效价在MND组为289.20±183.66,明显高于OND组(97.50±60)及NC组(<50),抗体效价>350时,仅见于MND组,各类MND的GM_1抗体阳性数及效价以下运动神经元病(LMND)最高,肌萎缩侧束硬化(ALS)次之,上运动神经元病(UMND)最低,GM_1抗体效价与病情相关(P<0.01),病情重、效价高。
The positive rate of IgM-ganglioside GM1 in serum of 26 patients with motor neuropathy (MND) was 65%, which was significantly higher than that of 11% of other neuropathy (OND) patients and normal people (NC). The antibody titer in MND group was 289.20 ± 183.66, which was significantly higher than that in OND group (97.50 ± 60) and NC group (<50). The titer of antibody was only found in MND group, The titer was the highest in motor neuron disease (LMND), followed by amyotrophic lateral sclerosis (ALS), the lowest in motor neuron disease (UMND), and the GM_1 antibody titer was associated with the disease (P <0.01) High price.