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一、妊娠时的药物应用1.药物对妊娠母体的影响:对妊娠母体投药时应注意观察与妊娠这一特殊生理状态所致的副作用的出现。妊娠、分娩虽然是一生理现象,但对母体也是一较大的负荷,在妊娠时机体内的代谢机能均呈亢进状态,也增加了肝肾的负担,故对药物的代谢、吸收机能比非妊娠对有很大的变化,特别是对其处理及排泻能力均低下,其药物的副作用出现率也比非妊娠时为高。故在妊娠时,一般药物给予较小剂量即能发挥药效,其作用的持续时间也相应的延长,而给予相对的大剂量时,即可出现有害的副作用。2.药物对胎儿、新生儿的影响:药物对胎儿及
First, the application of drugs during pregnancy 1. The impact of drugs on pregnant mothers: the mother of the pregnancy should pay attention to observe the administration and pregnancy, the occurrence of this special physiological state of the side effects. Pregnancy, childbirth is a physiological phenomenon, but also a more significant load on the mother, during pregnancy, the body’s metabolic function were hyperthyroidism, but also increased the burden on the liver and kidney, so the metabolism of drugs, the absorption of non-pregnancy than non-pregnancy Significant changes were observed, especially with regard to their low ability to handle and discharge, and their drug side effects were higher than those at non-pregnancy. Therefore, in pregnancy, the general drug to give a smaller dose that can play a pharmacodynamic effect of the duration of the corresponding extension, and given a relatively large dose, you can have harmful side effects. 2. The impact of drugs on the fetus, newborn: drugs on the fetus and