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目的探讨雷帕霉素药物洗脱支架(cypherTM)在老年人急性ST段抬高心肌梗死(STEMI)急诊经皮冠状动脉介入治疗(PCI)中应用的安全性和有效性。方法对51例年龄≥70岁(77.4±6.3)岁STEMI 51处罪犯病变行急诊PCI治疗,共植入cypherTM54枚。结果51例介入治疗患者均获成功,未发生与介入治疗有关的并发症。1例于术后18 h死于心源性休克,未发生其余心血管事件。随后进行了6~18(8.1±5.6)个月临床随访,1例术后3个月发生猝死,另有1例术后5个月再次行冠状动脉血运重建术,无其余心血管事件发生。结论cypherTM在老年人STE-MI急诊PCI的应用中有较强的安全性和有效性。
Objective To investigate the safety and efficacy of the cyprapramycin-eluting stent (cypherTM) in elderly patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI). Methods Totally 51 cases of STEMI 51 cases of age ≥70 years (77.4 ± 6.3) were treated with emergency PCI, and a total of 54 cypherTM were implanted. Results 51 patients were successful in interventional therapy, no complications related to interventional therapy. One patient died of cardiogenic shock at 18 hours after operation, and no other cardiovascular events occurred. Followed by 6 to 18 (8.1 ± 5.6) months of clinical follow-up, 1 case of sudden death occurred 3 months after surgery, while another 1 5 months after coronary revascularization again without any other cardiovascular events . Conclusion cypherTM is safe and effective in the emergency PCI of elderly patients with STE-MI.